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The molecular targets of approved treatments for pulmonary arterial hypertension

Until recently, three classes of medical therapy were available for the treatment of pulmonary arterial hypertension (PAH)—prostanoids, endothelin receptor antagonists and phosphodiesterase type 5 (PDE5) inhibitors. With the approval of the soluble guanylate cyclase stimulator riociguat, an addition...

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Detalles Bibliográficos
Autores principales: Humbert, Marc, Ghofrani, Hossein-Ardeschir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717417/
https://www.ncbi.nlm.nih.gov/pubmed/26219978
http://dx.doi.org/10.1136/thoraxjnl-2015-207170