Global translational impacts of the loss of the tRNA modification t(6)A in yeast

The universal tRNA modification t(6)A is found at position 37 of nearly all tRNAs decoding ANN codons. The absence of t(6)A(37) leads to severe growth defects in baker’s yeast, phenotypes similar to those caused by defects in mcm(5)s(2)U(34) synthesis. Mutants in mcm(5)s(2)U(34) can be suppressed by...

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Detalles Bibliográficos
Autores principales: Thiaville, Patrick C., Legendre, Rachel, Rojas-Benítez, Diego, Baudin-Baillieu, Agnès, Hatin, Isabelle, Chalancon, Guilhem, Glavic, Alvaro, Namy, Olivier, de Crécy-Lagard, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2015
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717488/
https://www.ncbi.nlm.nih.gov/pubmed/26798630
http://dx.doi.org/10.15698/mic2016.01.473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717488/
https://www.ncbi.nlm.nih.gov/pubmed/26798630
http://dx.doi.org/10.15698/mic2016.01.473

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