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Endogenous adaptation to low oxygen modulates T-cell regulatory pathways in EAE

BACKGROUND: In the brain, chronic inflammatory activity may lead to compromised delivery of oxygen and glucose suggesting that therapeutic approaches aimed at restoring metabolic balance may be useful. In vivo exposure to chronic mild normobaric hypoxia (10 % oxygen) leads to a number of endogenous...

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Detalles Bibliográficos
Autores principales: Esen, Nilufer, Katyshev, Vladimir, Serkin, Zakhar, Katysheva, Svetlana, Dore-Duffy, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717549/
https://www.ncbi.nlm.nih.gov/pubmed/26785841
http://dx.doi.org/10.1186/s12974-015-0407-4