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Genetic heterogeneity of actionable genes between primary and metastatic tumor in lung adenocarcinoma

BACKGROUND: Biopsy for lung cancer diagnosis is usually done at a single site. But it is unclear that genetic information at one biopsy site represents that of other lesions and is sufficient for therapeutic decision making. METHODS: Non-synonymous mutations and insertions/deletions of 16 genes cont...

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Detalles Bibliográficos
Autores principales: Kim, Eun Young, Cho, Eun Na, Park, Heae Surng, Kim, Arum, Hong, Ji Young, Lim, Seri, Youn, Jong Pil, Hwang, Seung Yong, Chang, Yoon Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717557/
https://www.ncbi.nlm.nih.gov/pubmed/26782967
http://dx.doi.org/10.1186/s12885-016-2049-z