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Genetic heterogeneity of actionable genes between primary and metastatic tumor in lung adenocarcinoma
BACKGROUND: Biopsy for lung cancer diagnosis is usually done at a single site. But it is unclear that genetic information at one biopsy site represents that of other lesions and is sufficient for therapeutic decision making. METHODS: Non-synonymous mutations and insertions/deletions of 16 genes cont...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717557/ https://www.ncbi.nlm.nih.gov/pubmed/26782967 http://dx.doi.org/10.1186/s12885-016-2049-z |