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Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson’s disease

BACKGROUND: Despite decades of intensive research, to date, there is no accepted diagnosis for Parkinson’s disease (PD) based on biochemical analysis of blood or CSF. However, neurodegeneration in the brains of PD patients begins several years before the manifestation of the clinical symptoms, point...

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Detalles Bibliográficos
Autores principales: Majbour, Nour K., Vaikath, Nishant N., van Dijk, Karin D., Ardah, Mustafa T., Varghese, Shiji, Vesterager, Louise B., Montezinho, Liliana P., Poole, Stephen, Safieh-Garabedian, Bared, Tokuda, Takahiko, Teunissen, Charlotte E., Berendse, Henk W., van de Berg, Wilma D. J., El-Agnaf, Omar M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717559/
https://www.ncbi.nlm.nih.gov/pubmed/26782965
http://dx.doi.org/10.1186/s13024-016-0072-9