The prognostic effect of PTEN expression status in colorectal cancer development and evaluation of factors affecting it: miR-21 and promoter methylation

BACKGROUND: PTEN is a tumor suppressor gene which is involved in cellular proliferation, differentiation, and apoptosis. Loss or down-regulation of PTEN plays an important role in human cancers development. In this study, we investigated the effect of miR-21 and promoter methylation on the PTEN expr...

Descripción completa

Detalles Bibliográficos
Autores principales: Yazdani, Yaghoub, Farazmandfar, Touraj, Azadeh, Hossein, Zekavatian, Zeinab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717643/
https://www.ncbi.nlm.nih.gov/pubmed/26787105
http://dx.doi.org/10.1186/s12929-016-0228-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717643/
https://www.ncbi.nlm.nih.gov/pubmed/26787105
http://dx.doi.org/10.1186/s12929-016-0228-5

Ejemplares similares