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The prognostic effect of PTEN expression status in colorectal cancer development and evaluation of factors affecting it: miR-21 and promoter methylation

BACKGROUND: PTEN is a tumor suppressor gene which is involved in cellular proliferation, differentiation, and apoptosis. Loss or down-regulation of PTEN plays an important role in human cancers development. In this study, we investigated the effect of miR-21 and promoter methylation on the PTEN expr...

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Detalles Bibliográficos
Autores principales:	Yazdani, Yaghoub, Farazmandfar, Touraj, Azadeh, Hossein, Zekavatian, Zeinab
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717643/ https://www.ncbi.nlm.nih.gov/pubmed/26787105 http://dx.doi.org/10.1186/s12929-016-0228-5

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