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Macrophage‐mediated cholesterol handling in atherosclerosis

Formation of foam cells is a hallmark at the initial stages of atherosclerosis. Monocytes attracted by pro‐inflammatory stimuli attach to the inflamed vascular endothelium and penetrate to the arterial intima where they differentiate to macrophages. Intimal macrophages phagocytize oxidized low‐densi...

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Detalles Bibliográficos
Autores principales: Chistiakov, Dimitry A., Bobryshev, Yuri V., Orekhov, Alexander N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717859/
https://www.ncbi.nlm.nih.gov/pubmed/26493158
http://dx.doi.org/10.1111/jcmm.12689