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Macrophage‐mediated cholesterol handling in atherosclerosis
Formation of foam cells is a hallmark at the initial stages of atherosclerosis. Monocytes attracted by pro‐inflammatory stimuli attach to the inflamed vascular endothelium and penetrate to the arterial intima where they differentiate to macrophages. Intimal macrophages phagocytize oxidized low‐densi...
Autores principales: | Chistiakov, Dimitry A., Bobryshev, Yuri V., Orekhov, Alexander N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717859/ https://www.ncbi.nlm.nih.gov/pubmed/26493158 http://dx.doi.org/10.1111/jcmm.12689 |
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