Cargando…

Prolonged silencing of diacylglycerol acyltransferase‐1 induces a dedifferentiated phenotype in human liver cells

Diacylglycerol acyltransferase‐1 (DGAT1), a key enzyme in triglyceride (TG) biogenesis, is highly associated with metabolic abnormalities, such as obesity and type 2 diabetes. However, the effects of DGAT1 silencing in the human liver have not been elucidated. To investigate the effects of DGAT1 sil...

Descripción completa

Detalles Bibliográficos
Autores principales: Chang, Soyoung, Sung, Pil Soo, Lee, Jungsul, Park, Junseong, Shin, Eui‐Cheol, Choi, Chulhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717863/
https://www.ncbi.nlm.nih.gov/pubmed/26493024
http://dx.doi.org/10.1111/jcmm.12685