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Prolonged silencing of diacylglycerol acyltransferase‐1 induces a dedifferentiated phenotype in human liver cells
Diacylglycerol acyltransferase‐1 (DGAT1), a key enzyme in triglyceride (TG) biogenesis, is highly associated with metabolic abnormalities, such as obesity and type 2 diabetes. However, the effects of DGAT1 silencing in the human liver have not been elucidated. To investigate the effects of DGAT1 sil...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717863/ https://www.ncbi.nlm.nih.gov/pubmed/26493024 http://dx.doi.org/10.1111/jcmm.12685 |