P2X7 Receptor Antagonism Attenuates the Intermittent Hypoxia-induced Spatial Deficits in a Murine Model of Sleep Apnea Via Inhibiting Neuroinflammation and Oxidative Stress

BACKGROUND: The mechanism of the neural injury caused by chronic intermittent hypoxia (CIH) that characterizes obstructive sleep apnea syndrome (OSAS) is not clearly known. The purpose of this study was to investigate whether P2X7 receptor (P2X7R) is responsible for the CIH-induced neural injury and...

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Detalles Bibliográficos
Autores principales: Deng, Yan, Guo, Xue-Ling, Yuan, Xiao, Shang, Jin, Zhu, Die, Liu, Hui-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717977/
https://www.ncbi.nlm.nih.gov/pubmed/26265609
http://dx.doi.org/10.4103/0366-6999.162495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717977/
https://www.ncbi.nlm.nih.gov/pubmed/26265609
http://dx.doi.org/10.4103/0366-6999.162495

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