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MicroRNAs in fibrosis: opportunities and challenges

MicroRNAs (miRNAs) are small, non-coding RNAs that mediate mRNA cleavage, translational repression or mRNA destabilisation and are around 22–25 nucleotides in length via partial complementary binding to the 3′ untranslated region in target transcripts. They are master regulators of gene expression....

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Detalles Bibliográficos
Autor principal: O’Reilly, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718015/
https://www.ncbi.nlm.nih.gov/pubmed/26762516
http://dx.doi.org/10.1186/s13075-016-0929-x