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MicroRNAs in fibrosis: opportunities and challenges
MicroRNAs (miRNAs) are small, non-coding RNAs that mediate mRNA cleavage, translational repression or mRNA destabilisation and are around 22–25 nucleotides in length via partial complementary binding to the 3′ untranslated region in target transcripts. They are master regulators of gene expression....
Autor principal: | O’Reilly, Steven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718015/ https://www.ncbi.nlm.nih.gov/pubmed/26762516 http://dx.doi.org/10.1186/s13075-016-0929-x |
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