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Transient receptor potential ankyrin 1 (TRPA1) receptor is involved in chronic arthritis: in vivo study using TRPA1-deficient mice

BACKGROUND: The transient receptor potential ankyrin 1 (TRPA1) is a calcium-permeable cation channel that is expressed on capsaicin-sensitive sensory neurons, endothelial and inflammatory cells. It is activated by a variety of inflammatory mediators, such as methylglyoxal, formaldehyde and hydrogen...

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Detalles Bibliográficos
Autores principales: Horváth, Ádám, Tékus, Valéria, Boros, Melinda, Pozsgai, Gábor, Botz, Bálint, Borbély, Éva, Szolcsányi, János, Pintér, Erika, Helyes, Zsuzsanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718022/
https://www.ncbi.nlm.nih.gov/pubmed/26746673
http://dx.doi.org/10.1186/s13075-015-0904-y