New insights into the regulation of innate immunity by caspase-8

Caspase-8 is required for extrinsic apoptosis, but is also central for preventing a pro-inflammatory receptor interacting protein kinase (RIPK) 3–mixed lineage kinase domain-like (MLKL)-dependent cell death pathway termed necroptosis. Despite these critical cellular functions, the impact of capase-8...

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Detalles Bibliográficos
Autores principales: Sagulenko, Vitaliya, Lawlor, Kate E., Vince, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718034/
https://www.ncbi.nlm.nih.gov/pubmed/26757916
http://dx.doi.org/10.1186/s13075-015-0910-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718034/
https://www.ncbi.nlm.nih.gov/pubmed/26757916
http://dx.doi.org/10.1186/s13075-015-0910-0

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