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Recent transcriptome-wide mapping of UPF1 binding sites reveals evidence for its recruitment to mRNA before translation
The ATP-dependent RNA helicase UPF1, a key factor in nonsense-mediated mRNA decay (NMD), was so far thought to be recruited specifically to NMD-targeted mRNAs by aberrantly terminating ribosomes. However, two recent publications reporting independently transcriptome-wide mapping of UPF1 occupancy on...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718051/ https://www.ncbi.nlm.nih.gov/pubmed/26824025 http://dx.doi.org/10.4161/trla.26977 |