4E-BP restrains eIF4E phosphorylation

In eukaryotes, mRNA translation is dependent on the cap-binding protein eIF4E. Through its simultaneous interaction with the mRNA cap structure and with the ribosome-associated eIF4G adaptor protein, eIF4E physically posits the ribosome at the 5′ extremity of capped mRNA. eIF4E activity is regulated...

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Detalles Bibliográficos
Autores principales: Müller, David, Lasfargues, Charline, El Khawand, Sally, Alard, Amandine, Schneider, Robert J., Bousquet, Corinne, Pyronnet, Stéphane, Martineau, Yvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2013
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718053/
https://www.ncbi.nlm.nih.gov/pubmed/26824022
http://dx.doi.org/10.4161/trla.25819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718053/
https://www.ncbi.nlm.nih.gov/pubmed/26824022
http://dx.doi.org/10.4161/trla.25819

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