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Clearance of yeast eRF-3 prion [PSI+] by amyloid enlargement due to the imbalance between chaperone Ssa1 and cochaperone Sgt2

The cytoplasmic [PSI+] element of budding yeast represents the prion conformation of translation release factor eRF-3 (Sup35). Prions are transmissible agents caused by self-seeded highly ordered aggregates (amyloids). Much interest lies in understanding how prions are developed and transmitted. How...

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Detalles Bibliográficos
Autores principales: Arai, Chie, Kurahashi, Hiroshi, Pack, Chan-Gi, Sako, Yasushi, Nakamura, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718058/
https://www.ncbi.nlm.nih.gov/pubmed/26824024
http://dx.doi.org/10.4161/trla.26574