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Re-analysis of genome wide data on mammalian microRNA-mediated suppression of gene expression

microRNAs are short endogenously expressed RNAs that regulate gene expression post-transcriptionally. Although both mRNA degradation and suppression of mRNA translation can mediate reduced protein levels following microRNA targeting of an mRNA, their relative contributions have remained elusive. A r...

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Detalles Bibliográficos
Autores principales: Larsson, Ola, Nadon, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718065/
https://www.ncbi.nlm.nih.gov/pubmed/26824020
http://dx.doi.org/10.4161/trla.24557