Cargando…

Dual use of GTP hydrolysis by elongation factor G on the ribosome

Elongation factor G (EF-G) is a GTPase that catalyzes tRNA and mRNA translocation during the elongation cycle of protein synthesis. The GTP-bound state of the factor on the ribosome has been studied mainly with non-hydrolyzable analogs of GTP, which led to controversial conclusions about the role of...

Descripción completa

Detalles Bibliográficos
Autores principales: Cunha, Carlos E., Belardinelli, Riccardo, Peske, Frank, Holtkamp, Wolf, Wintermeyer, Wolfgang, Rodnina, Marina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718068/
https://www.ncbi.nlm.nih.gov/pubmed/26824016
http://dx.doi.org/10.4161/trla.24315