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KLF4 is a key determinant in the development and progression of cerebral cavernous malformations

Cerebral cavernous malformations (CCMs) are vascular malformations located within the central nervous system often resulting in cerebral hemorrhage. Pharmacological treatment is needed, since current therapy is limited to neurosurgery. Familial CCM is caused by loss‐of‐function mutations in any of C...

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Detalles Bibliográficos
Autores principales: Cuttano, Roberto, Rudini, Noemi, Bravi, Luca, Corada, Monica, Giampietro, Costanza, Papa, Eleanna, Morini, Marco Francesco, Maddaluno, Luigi, Baeyens, Nicolas, Adams, Ralf H, Jain, Mukesh K, Owens, Gary K, Schwartz, Martin, Lampugnani, Maria Grazia, Dejana, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718159/
https://www.ncbi.nlm.nih.gov/pubmed/26612856
http://dx.doi.org/10.15252/emmm.201505433