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Loss of BAP1 Expression Occurs Frequently in Intrahepatic Cholangiocarcinoma

BRCA1-associated protein 1 (BAP1) is a deubiquitinating enzyme that functions as a tumor suppressor gene. Double hit BAP1 inactivation has been reported in a range of tumor types, including intrahepatic cholangiocarcinoma (ICC), sometimes in association with germline mutation. We performed immunohis...

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Detalles Bibliográficos
Autores principales: Andrici, Juliana, Goeppert, Benjamin, Sioson, Loretta, Clarkson, Adele, Renner, Marcus, Stenzinger, Albrecht, Tayao, Michael, Watson, Nicole, Farzin, Mahtab, Toon, Christopher W., Smith, Ross C., Mittal, Anubhav, Samra, Jaswinder S., Hugh, Thomas J., Chou, Angela, Lawlor, Rita T., Weichert, Wilko, Schirmacher, Peter, Sperandio, Nicola, Ruzzenente, Andrea, Scarpa, Aldo, Gill, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718285/
https://www.ncbi.nlm.nih.gov/pubmed/26765459
http://dx.doi.org/10.1097/MD.0000000000002491