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ApoE4 upregulates the activity of mitochondria‐associated ER membranes

In addition to the appearance of senile plaques and neurofibrillary tangles, Alzheimer's disease (AD) is characterized by aberrant lipid metabolism and early mitochondrial dysfunction. We recently showed that there was increased functionality of mitochondria‐associated endoplasmic reticulum (ER...

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Detalles Bibliográficos
Autores principales: Tambini, Marc D, Pera, Marta, Kanter, Ellen, Yang, Hua, Guardia‐Laguarta, Cristina, Holtzman, David, Sulzer, David, Area‐Gomez, Estela, Schon, Eric A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718413/
https://www.ncbi.nlm.nih.gov/pubmed/26564908
http://dx.doi.org/10.15252/embr.201540614