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Hypothyroidism Side Effect in Patients Treated with Sunitinib or Sorafenib: Clinical and Structural Analyses

Tyrosine kinase inhibitors (TKIs) provide more effective targeted treatments for cancer, but are subject to a variety of adverse effects, such as hypothyroidism. TKI-induced hypothyroidism is a highly complicated issue, because of not only the unrealized toxicological mechanisms, but also different...

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Detalles Bibliográficos
Autores principales: Shu, Mao, Zai, Xiaoli, Zhang, Beina, Wang, Rui, Lin, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718448/
https://www.ncbi.nlm.nih.gov/pubmed/26784451
http://dx.doi.org/10.1371/journal.pone.0147048