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Nucleotide-binding mechanisms in pseudokinases

Pseudokinases are classified by the lack of one or several of the highly conserved motifs involved in nucleotide (nt) binding or catalytic activity of protein kinases (PKs). Pseudokinases represent ∼10% of the human kinome and they are found in all evolutionary classes of kinases. It has become evid...

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Detalles Bibliográficos
Autores principales: Hammarén, Henrik M., Virtanen, Anniina T., Silvennoinen, Olli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718504/
https://www.ncbi.nlm.nih.gov/pubmed/26589967
http://dx.doi.org/10.1042/BSR20150226