Shugoshin-1 Balances Aurora B Kinase Activity via PP2A to Promote Chromosome Bi-orientation

Correction of faulty kinetochore-microtubule attachments is essential for faithful chromosome segregation and dictated by the opposing activities of Aurora B kinase and PP1 and PP2A phosphatases. How kinase and phosphatase activities are appropriately balanced is less clear. Here, we show that a cen...

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Detalles Bibliográficos
Autores principales: Meppelink, Amanda, Kabeche, Lilian, Vromans, Martijn J.M., Compton, Duane A., Lens, Susanne M.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718550/
https://www.ncbi.nlm.nih.gov/pubmed/25892238
http://dx.doi.org/10.1016/j.celrep.2015.03.052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718550/
https://www.ncbi.nlm.nih.gov/pubmed/25892238
http://dx.doi.org/10.1016/j.celrep.2015.03.052

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