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Integrator mediates the biogenesis of enhancer RNAs

Integrator is a multi-subunit complex stably associated with the C-terminal domain (CTD) of RNA polymerase II (RNAPII) (1). Integrator is endowed with a core catalytic RNA endonuclease activity, which is required for the 3′-end processing of non-polyadenylated RNAPII-dependent uridylate-rich small n...

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Detalles Bibliográficos
Autores principales: Lai, Fan, Gardini, Alessandro, Zhang, Anda, Shiekhattar, Ramin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718573/
https://www.ncbi.nlm.nih.gov/pubmed/26308897
http://dx.doi.org/10.1038/nature14906