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Integrator mediates the biogenesis of enhancer RNAs
Integrator is a multi-subunit complex stably associated with the C-terminal domain (CTD) of RNA polymerase II (RNAPII) (1). Integrator is endowed with a core catalytic RNA endonuclease activity, which is required for the 3′-end processing of non-polyadenylated RNAPII-dependent uridylate-rich small n...
Autores principales: | Lai, Fan, Gardini, Alessandro, Zhang, Anda, Shiekhattar, Ramin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718573/ https://www.ncbi.nlm.nih.gov/pubmed/26308897 http://dx.doi.org/10.1038/nature14906 |
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