mTOR-Dependent and Independent Survival Signaling by PI3K in B Lymphocytes

Peripheral B lymphocyte survival requires the B cell receptor (BCR) and B cell activating factor (BAFF) binding to its receptor (BAFF-R). Deletion of the BCR, or its signal transducing chaperone Igβ, leads to rapid loss of mature B cells, indicating that signals initiated at the BCR are crucial for...

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Detalles Bibliográficos
Autores principales: Kaileh, Mary, Vazquez, Estefania, MacFarlane, Alexander W., Campbell, Kerry, Kurosaki, Tomohiro, Siebenlist, Ulrich, Sen, Ranjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718598/
https://www.ncbi.nlm.nih.gov/pubmed/26785352
http://dx.doi.org/10.1371/journal.pone.0146955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718598/
https://www.ncbi.nlm.nih.gov/pubmed/26785352
http://dx.doi.org/10.1371/journal.pone.0146955

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