In Vitro Comparison of the Activity Requirements and Substrate Specificity of Human and Triboleum castaneum PINK1 Orthologues

Mutations in the gene encoding the mitochondrial kinase PINK1 cause early-onset familial Parkinson’s disease. To understand the biological function of PINK1 and its role in the pathogenesis of Parkinson’s disease, it is useful to study its kinase activity towards substrates both in vivo and in vitro...

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Detalles Bibliográficos
Autores principales: Aerts, Liesbeth, Craessaerts, Katleen, De Strooper, Bart, Morais, Vanessa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718624/
https://www.ncbi.nlm.nih.gov/pubmed/26784449
http://dx.doi.org/10.1371/journal.pone.0146083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718624/
https://www.ncbi.nlm.nih.gov/pubmed/26784449
http://dx.doi.org/10.1371/journal.pone.0146083

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