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Striking HIV-1 Entry by Targeting HIV-1 gp41. But, Where Should We Target?
HIV-1 gp41 facilitates the viral fusion through a conformational switch involving the association of three C-terminal helices along the conserved hydrophobic grooves of three N-terminal helices coiled-coil. The control of these structural rearrangements is thought to be central to HIV-1 entry and, t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718650/ https://www.ncbi.nlm.nih.gov/pubmed/26785380 http://dx.doi.org/10.1371/journal.pone.0146743 |