Cargando…

Striking HIV-1 Entry by Targeting HIV-1 gp41. But, Where Should We Target?

HIV-1 gp41 facilitates the viral fusion through a conformational switch involving the association of three C-terminal helices along the conserved hydrophobic grooves of three N-terminal helices coiled-coil. The control of these structural rearrangements is thought to be central to HIV-1 entry and, t...

Descripción completa

Detalles Bibliográficos
Autores principales: Teixeira, Cátia, Barbault, Florent, Couesnon, Thierry, Gomes, José R. B., Gomes, Paula, Maurel, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718650/
https://www.ncbi.nlm.nih.gov/pubmed/26785380
http://dx.doi.org/10.1371/journal.pone.0146743