Interleukin-22 Alleviated Palmitate-Induced Endoplasmic Reticulum Stress in INS-1 Cells through Activation of Autophagy

OBJECTIVE: Stimulation with saturated fatty acids has been shown to induce oxidative stress and endoplasmic reticulum (ER) stress in β cells and has been recognized as an important component of the pathogenesis of type 2 diabetes (T2D). Interleukin-22 (IL-22) plays a critical role in preventing β ce...

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Detalles Bibliográficos
Autores principales: Hu, Minling, Yang, Shuangli, Yang, Li, Cheng, Yanzhen, Zhang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718676/
https://www.ncbi.nlm.nih.gov/pubmed/26784895
http://dx.doi.org/10.1371/journal.pone.0146818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718676/
https://www.ncbi.nlm.nih.gov/pubmed/26784895
http://dx.doi.org/10.1371/journal.pone.0146818

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