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Interleukin-22 Alleviated Palmitate-Induced Endoplasmic Reticulum Stress in INS-1 Cells through Activation of Autophagy
OBJECTIVE: Stimulation with saturated fatty acids has been shown to induce oxidative stress and endoplasmic reticulum (ER) stress in β cells and has been recognized as an important component of the pathogenesis of type 2 diabetes (T2D). Interleukin-22 (IL-22) plays a critical role in preventing β ce...
Autores principales: | Hu, Minling, Yang, Shuangli, Yang, Li, Cheng, Yanzhen, Zhang, Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718676/ https://www.ncbi.nlm.nih.gov/pubmed/26784895 http://dx.doi.org/10.1371/journal.pone.0146818 |
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