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Depletion of Paraspeckle Protein 1 Enhances Methyl Methanesulfonate-Induced Apoptosis through Mitotic Catastrophe

Previously, we have shown that paraspeckle protein 1 (PSPC1), a protein component of paraspeckles that was involved in cisplatin-induced DNA damage response (DDR), probably functions at the G1/S checkpoint. In the current study, we further examined the role of PSPC1 in another DNA-damaging agent, me...

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Detalles Bibliográficos
Autores principales: Gao, Xiangjing, Zhang, Guanglin, Shan, Shigang, Shang, Yunlong, Chi, Linfeng, Li, Hongjuan, Cao, Yifei, Zhu, Xinqiang, Zhang, Meibian, Yang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718682/
https://www.ncbi.nlm.nih.gov/pubmed/26785254
http://dx.doi.org/10.1371/journal.pone.0146952