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Serum Amyloid A Induces Toll-Like Receptor 2-Dependent Inflammatory Cytokine Expression and Atrophy in C2C12 Skeletal Muscle Myotubes

BACKGROUND: Skeletal muscle wasting is an important comorbidity of Chronic Obstructive Pulmonary Disease (COPD) and is strongly correlated with morbidity and mortality. Patients who experience frequent acute exacerbations of COPD (AECOPD) have more severe muscle wasting and reduced recovery of muscl...

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Detalles Bibliográficos
Autores principales: Passey, Samantha L., Bozinovski, Steven, Vlahos, Ross, Anderson, Gary P., Hansen, Michelle J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718684/
https://www.ncbi.nlm.nih.gov/pubmed/26784349
http://dx.doi.org/10.1371/journal.pone.0146882