Fine-tuning citrate synthase flux potentiates and refines metabolic innovation in the Lenski evolution experiment

Evolutionary innovations that enable organisms to colonize new ecological niches are rare compared to gradual evolutionary changes in existing traits. We discovered that key mutations in the gltA gene, which encodes citrate synthase (CS), occurred both before and after Escherichia coli gained the ab...

Descripción completa

Detalles Bibliográficos
Autores principales: Quandt, Erik M, Gollihar, Jimmy, Blount, Zachary D, Ellington, Andrew D, Georgiou, George, Barrick, Jeffrey E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Genomics and Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718724/
https://www.ncbi.nlm.nih.gov/pubmed/26465114
http://dx.doi.org/10.7554/eLife.09696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718724/
https://www.ncbi.nlm.nih.gov/pubmed/26465114
http://dx.doi.org/10.7554/eLife.09696

Ejemplares similares