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Fine-tuning citrate synthase flux potentiates and refines metabolic innovation in the Lenski evolution experiment
Evolutionary innovations that enable organisms to colonize new ecological niches are rare compared to gradual evolutionary changes in existing traits. We discovered that key mutations in the gltA gene, which encodes citrate synthase (CS), occurred both before and after Escherichia coli gained the ab...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718724/ https://www.ncbi.nlm.nih.gov/pubmed/26465114 http://dx.doi.org/10.7554/eLife.09696 |