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Mechanical sensitivity of Piezo1 ion channels can be tuned by cellular membrane tension
Piezo1 ion channels mediate the conversion of mechanical forces into electrical signals and are critical for responsiveness to touch in metazoans. The apparent mechanical sensitivity of Piezo1 varies substantially across cellular environments, stimulating methods and protocols, raising the fundament...
Autores principales: | Lewis, Amanda H, Grandl, Jörg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718726/ https://www.ncbi.nlm.nih.gov/pubmed/26646186 http://dx.doi.org/10.7554/eLife.12088 |
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