An essential role of acetylcholine-glutamate synergy at habenular synapses in nicotine dependence

A great deal of interest has been focused recently on the habenula and its critical role in aversion, negative-reward and drug dependence. Using a conditional mouse model of the ACh-synthesizing enzyme choline acetyltransferase (Chat), we report that local elimination of acetylcholine (ACh) in media...

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Detalles Bibliográficos
Autores principales: Frahm, Silke, Antolin-Fontes, Beatriz, Görlich, Andreas, Zander, Johannes-Friedrich, Ahnert-Hilger, Gudrun, Ibañez-Tallon, Ines
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718731/
https://www.ncbi.nlm.nih.gov/pubmed/26623516
http://dx.doi.org/10.7554/eLife.11396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718731/
https://www.ncbi.nlm.nih.gov/pubmed/26623516
http://dx.doi.org/10.7554/eLife.11396

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