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An essential role of acetylcholine-glutamate synergy at habenular synapses in nicotine dependence
A great deal of interest has been focused recently on the habenula and its critical role in aversion, negative-reward and drug dependence. Using a conditional mouse model of the ACh-synthesizing enzyme choline acetyltransferase (Chat), we report that local elimination of acetylcholine (ACh) in media...
Autores principales: | Frahm, Silke, Antolin-Fontes, Beatriz, Görlich, Andreas, Zander, Johannes-Friedrich, Ahnert-Hilger, Gudrun, Ibañez-Tallon, Ines |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718731/ https://www.ncbi.nlm.nih.gov/pubmed/26623516 http://dx.doi.org/10.7554/eLife.11396 |
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