“Deadman” and “Passcode” microbial kill switches for bacterial containment

Biocontainment systems that couple environmental sensing with circuit-based control of cell viability could be used to prevent escape of genetically modified microbes into the environment. Here we present two engineered safe-guard systems: the Deadman and Passcode kill switches. The Deadman kill swi...

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Detalles Bibliográficos
Autores principales: Chan, Clement T. Y., Lee, Jeong Wook, Cameron, D. Ewen, Bashor, Caleb J., Collins, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718764/
https://www.ncbi.nlm.nih.gov/pubmed/26641934
http://dx.doi.org/10.1038/nchembio.1979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718764/
https://www.ncbi.nlm.nih.gov/pubmed/26641934
http://dx.doi.org/10.1038/nchembio.1979

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