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α-MHC MitoTimer mouse: In vivo mitochondrial turnover model reveals remarkable mitochondrial heterogeneity in the heart

In order to maintain an efficient, energy-producing network in the heart, dysfunctional mitochondria are cleared through the mechanism of autophagy, which is closely linked with mitochondrial biogenesis; these, together with fusion and fission comprise a crucial process known as mitochondrial turnov...

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Detalles Bibliográficos
Autores principales: Stotland, Aleksandr, Gottlieb, Roberta A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718850/
https://www.ncbi.nlm.nih.gov/pubmed/26654779
http://dx.doi.org/10.1016/j.yjmcc.2015.11.032