Polyclonal CD4(+) T cell tolerance is established by distinct mechanisms, according to self-peptide expression patterns

Studies of mouse monoclonal CD4(+) T cell repertoires have revealed several mechanisms of self-tolerance, however, which mechanisms operate in normal repertoires is unclear. Here, polyclonal CD4(+) T cells specific for green fluorescent protein expressed in different organs were studied, allowing de...

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Detalles Bibliográficos
Autores principales: Malhotra, Deepali, Linehan, Jonathan L., Dileepan, Thamotharampillai, Lee, You Jeong, Purtha, Whitney E., Lu, Jennifer V., Nelson, Ryan W., Fife, Brian T., Orr, Harry T., Anderson, Mark S., Hogquist, Kristin A., Jenkins, Marc K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718891/
https://www.ncbi.nlm.nih.gov/pubmed/26726812
http://dx.doi.org/10.1038/ni.3327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718891/
https://www.ncbi.nlm.nih.gov/pubmed/26726812
http://dx.doi.org/10.1038/ni.3327

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