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Preclinical studies of 5-fluoro-2′-deoxycytidine and tetrahydrouridine in pediatric brain tumors

Chemotherapies active in preclinical studies frequently fail in the clinic due to lack of efficacy, which limits progress for rare cancers since only small numbers of patients are available for clinical trials. Thus, a preclinical drug development pipeline was developed to prioritize potentially act...

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Detalles Bibliográficos
Autores principales: Morfouace, Marie, Nimmervoll, Birgit, Boulos, Nidal, Patel, Yogesh T., Shelat, Anang, Freeman, Burgess B., Robinson, Giles W., Wright, Karen, Gajjar, Amar, Stewart, Clinton F., Gilbertson, Richard J., Roussel, Martine F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718940/
https://www.ncbi.nlm.nih.gov/pubmed/26518542
http://dx.doi.org/10.1007/s11060-015-1965-0