A simple nonradioactive method for the determination of the binding affinities of antibodies induced by hapten bioconjugates for drugs of abuse

The accurate analytical measurement of binding affinities of polyclonal antibody in sera to heroin, 6-acetylmorphine (6-AM), and morphine has been a challenging task. A simple nonradioactive method that uses deuterium-labeled drug tracers and equilibrium dialysis (ED) combined with ultra performance...

Descripción completa

Detalles Bibliográficos
Autores principales: Torres, Oscar B., Antoline, Joshua F. G., Li, Fuying, Jalah, Rashmi, Jacobson, Arthur E., Rice, Kenner C., Alving, Carl R., Matyas, Gary R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718952/
https://www.ncbi.nlm.nih.gov/pubmed/26677020
http://dx.doi.org/10.1007/s00216-015-9223-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718952/
https://www.ncbi.nlm.nih.gov/pubmed/26677020
http://dx.doi.org/10.1007/s00216-015-9223-z

Ejemplares similares