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Sox6 suppression induces RA-dependent apoptosis mediated by BMP-4 expression during neuronal differentiation in P19 cells

Sox6 is a transcription factor that induces neuronal differentiation in P19 cells; its suppression not only inhibits neuronal differentiation but also induces retinoic acid (RA)-dependent apoptosis of P19 cells. In the present study, we found that Sox6 suppression-induced apoptosis was mediated by a...

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Detalles Bibliográficos
Autores principales: Hamada-Kanazawa, Michiko, Ogawa, Daisuke, Takano, Masaoki, Miyake, Masaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718955/
https://www.ncbi.nlm.nih.gov/pubmed/26590087
http://dx.doi.org/10.1007/s11010-015-2607-8