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FoxO1 signaling plays a pivotal role in the cardiac telomere biology responses to calorie restriction

This study examined whether the forkhead transcription factors of O group 1 (FoxO1) might be involved in telomere biology during calorie restriction (CR). We used FoxO1-knockout heterozygous mice (FoxO1(+/−)) and wild-type mice (WT) as a control. Both WT and FoxO1(+/−) were subjected to ad libitum (...

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Detalles Bibliográficos
Autores principales: Makino, N., Oyama, J., Maeda, T., Koyanagi, M., Higuchi, Y., Shimokawa, I., Mori, N., Furuyama, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718961/
https://www.ncbi.nlm.nih.gov/pubmed/26708219
http://dx.doi.org/10.1007/s11010-015-2615-8