Smac Mimetic-Induced Upregulation of CCL2/MCP-1 Triggers Migration and Invasion of Glioblastoma Cells and Influences the Tumor Microenvironment in a Paracrine Manner()

Second mitochondria-derived activator of caspase (Smac) mimetics are considered as promising anticancer therapeutics that are currently under investigation in early clinical trials. They induce apoptosis by antagonizing inhibitor of apoptosis proteins, which are frequently overexpressed in cancer. W...

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Detalles Bibliográficos
Autores principales: Lindemann, Carina, Marschall, Viola, Weigert, Andreas, Klingebiel, Thomas, Fulda, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719005/
https://www.ncbi.nlm.nih.gov/pubmed/26152356
http://dx.doi.org/10.1016/j.neo.2015.05.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719005/
https://www.ncbi.nlm.nih.gov/pubmed/26152356
http://dx.doi.org/10.1016/j.neo.2015.05.002

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