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Denoising DNA deep sequencing data—high-throughput sequencing errors and their correction

Characterizing the errors generated by common high-throughput sequencing platforms and telling true genetic variation from technical artefacts are two interdependent steps, essential to many analyses such as single nucleotide variant calling, haplotype inference, sequence assembly and evolutionary s...

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Detalles Bibliográficos
Autores principales: Laehnemann, David, Borkhardt, Arndt, McHardy, Alice Carolyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719071/
https://www.ncbi.nlm.nih.gov/pubmed/26026159
http://dx.doi.org/10.1093/bib/bbv029